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Hunan China (Mainland) |
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Herbal Extract |
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Resveratrol 50%,90%,98%Giant Knotweed Extract Resveratrol Traditional Andmodernuses: Huzhang ("tiger cane") or giant knotweed is an east Asian species (Polygonum cuspidatum), belonging to the Polygonaceae family. Documented uses in traditional Chinese medicine date to the first century BC, and contemporary medical uses supported by clinical results include acute microbial infections or viral hepatitis, chemo- or radiation-induced leukocytopenia, atherosclerosis, and hyperlipidemia.Pharmacology: In animal experiments, huzhang has exhibited antitussive, antihistaminic, hypotensive, vasodilating, cytotoxic, and antioxidant properties, among others. Huzhang is also a concentrated source of resveratrol (3,5,4¡Â-trihydroxy stilbene), an antioxidant phenol produced in response to fungi. Resveratrol has also shown antimutagenic activity in bioassays conducted on bacteria in vitro (umu and Ames tests). And, in a recent investigation conducted in vivo and in vitro, resveratrol displayed chemopreventive effects at three critical stages of carcinogenesis. Specifically, resveratrol was found to 1) induce phase II drug metabolizing enzymes (antiinitiation); 2) mediate anti-inflammatory effects and inhibit cyclooxygenase and hydro-peroxidase (antipromotion); and 3) induce human promyelocytic leukemia cell diferentiation (antiprogression). Resveratrol was also found to inhibit the development of preneoplastic lesions in vitro and tumorigenesis in vivo. Very recently, it was reported that Huzhang extract is one of the best active-oxygen scavengers for the prevention of skin aging induced by UV-irradiation and free radical. Experiments conducted in vivo indicate that resveratrol is a potent vasodilator and inhibitor of platelet aggregation. Recent work in dogs and humans indicate that other concentrated sources of resveratrol (i.e., red wine and grape juice) eliminate cyclic blood-flow reductions caused by platelet-mediated thrombosis.Active Compounds: Huzhang is characterized by anthraquinones and their glycosides, napthoquinone, 3,5,4¡Â-trihydroxy stilbene (i.e., resveratrol), piceid, fallacinol, citreorosein, questin, questinol, protocatechuic acid, (+) catechin, 2,5-dimethyl-7- hydroxychromone, 7-hydroxy-4-methoxy-5-methylcoumarin, flavonols, polysaccharides, and condensed tannins.Regulatory Status: Under U.S. law, huzhang extract is regulated as a dietary supplement. As of this writing, no European governments had issued monographs or regulations for nutraceutical uses of huzhang. NOTE: The statements in this publication have not been evaluated by the FDA.Selected Reference: Encyclopedia of Chinese Drugs. Jiangsu Institute of Modern Medicine, Shanghai Scientific and Technical Publications, 1977. [Chinese] Encyclopedia of Common Natural Ingredients Used in Foods, Drugs, and Cosmetics, by Albert Leung, Ph.D. and Steven Foster. Hitoshi Masaki et al. Biol Pharm Bull. 18, 162-166, 1995. Huang WZ. Fujian Zhongyiyao, 18(4), 27, 1987. [Chinese] Kimura Y et al. Planta Med, 48, 164, 1996. Meishang Jang et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science, vol. 275, 218-220, 1997. Orsini, F. et al. Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-b-D glucopyranoside and related compounds. J Nat Prod. 60:1082-87, 1997. Pharmacognosy, Phytochemistry, Medicinal Plants, by Prof. Jean Bruneton. Lavoisier Tec & Doc/Intercept Ltd., 1995. Records of Chinese Materia Medica Vol. 1. Institute of Materia Medica, Chinese Academy of Sciences, 1982. [Chinese] Packing Detail Packed in paper-drums and two plastic-bags inside. Net Weight: 25kgs/drum. I.D. 40CmX50CM Storage Situation Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat. Shelf Life two years under well Storage situation and stored away from direct sun light. Changsha Nutramax Inc.(NM) is one of the leading manufacturer and exporter of the tea & herbal extracts in China, (Hunan Botanical Extracts Association of China), NM having certified ISO9000:2000, Kosher, cGMP. We have been manufacturing of exporting such products as Green Tea Extracts and Natural Botanical Extracts Series. Our major standardized products are Resveratrol 98%, Magnolia Bark Extract 95%, Baicalin 95%, Blueberry juice Concentrate Brix 65, Green Tea Extract 60% EGCG, Luo Han Guo Extract 80% .Mogrosides and Effective Component Monomer product such as Huperzine A 99%, Paclitaxel 99%, Artemisinine 99% , Rhynchophylline 98% and so on. We can supply about 240 kinds of Standardized Herbal Extracts and more 900 kinds of Botanical Extracts. Our products are in great demand and being exported to over 40 countries throughout the world.If you need other botanical extract, please visit NM's website.Welcome contact me for more detail inform. If you have any questions or suggestions, please don't hesitate to ask and tell me. With best wishes and personal regards!Best regards!Yours faithfully: Mr. smile zhang