proanthocyanidins (OPC) from grape seed extract active ingredients, pure natural bio-flavonoids substances. Proanthocyanidins is an essential biological anti-oxidants, a good water-soluble and can easily be absorbed by the body. As an antioxidant, anti-oxidative capacity is 20 times the vitamin C, vitamin E, 50 times, this is the greatest invention of this century one. The results show: proanthocyanidins (OPC) can go through the body's blood-brain barrier, the brain and nervous system have a good protective effect. Gets rid of free radicals due to significantly increase the artery and vein elasticity, prevent atherosclerosis by enhancing blood circulation and reduce blood viscosity and to prevent heart disease and other disorders. Make the skin maintain its elasticity and moisture, delaying production of wrinkles to achieve anti-aging purposes. Proanthocyanidins (opc) does not stimulate the gastrointestinal mucosa, very suitable for human consumption in patients with gastrointestinal diseases.