Griffonia Seed Extract (5-HTP)

Product Name: Griffonia Seeds Extract Botanical Name: Griffonia Simpicifolia Parts Used: Seeds Appearance: White or almost white well powder Standard Specifications: 10% 99% 5-HTP (HPLC) Molecular Formula: C11H12N2O3 Molecular Weight: 220.23 CAS NO.: 56-69-9 Constitutional Formula: 5-Hydroxytryptophan Pharmacology: The psychoactive action of 5-HTP is derived from its effect on the production of serotonin in central nervous system tissue. More specifically, 5-HTP increases the production of serotonin. Thus, it has been used to treat diseases, e.g. depression, for which the lack of serotonin is thought to be a contributing factor. Research shows that co-administration with carbidopa greatly increases plasma 5-HTP levels. However, several studies have reported that 5-HTP is effective even without a peripheral decarboxylase inhibitor (e.g. carbidopa). Other studies have indicated the risk of a scleroderma-like condition resulting from the combination of 5-HTP and carbidopa. 5-HTP also has been studied and shown to be of benefit in the following conditions: primary fibromyalgia syndrome,Friedreich’s ataxia, chronic headaches (primary or otherwise), depression, anxiety, binge eating associated with obesity, and insomnia.