Calcium Ascorbate (USP30/FCCV)

Calcium Ascorbate (USP30/FCCV)DESCRIPTION Calcium Ascorbate, the calcium salt of L-ascorbic acid (vitamin c) is white to yellowish, practically odorless powder.PROPERTIES Empirical Formula C12H14CaO122H2O Molecular Weight 426.35 Solubility Free soluble in water (approx.50 g/100 ml),slightly soluble in alcohol and insoluble in ether. pH of Solution 6.8-7.4(10% aqueous solution)APPLICATIONS Calcium Ascorbate is mostly used in dry preparations. Calcium Ascorbate solutions have a tendency to get a moisture up upon long standing. Calcium Ascorbate is generally recognized as safe (GRAS) as a chemical preservative (antioxidant). The proposed monograph on vitamin and mineral products for OCT human use in the Federal Register, March 16, 1979, lists Calcium Ascorbate (as well as sodium Ascorbate and Ascorbyl Palmitate) as accepted sources of vitamin c.COMPENDIAL REQUIREMENTSCalcium Ascorbate meets all requirements of FCC IV when tested according to those methods (pg.45-46).Identification Positive Assay (iodometric titration) Not less than 98.0% C12H14CaO122H2O Specific Rotation (α) 25 deg. +95 - +97deg. pH value 6.8 to 7.4 Loss on Drying Less than 0.1% Arsenic (as As) Max.3PPM Heavy Metal (as Pb) Max. 10PPM Fluoride Max. 10PPM Oxalate Pass test Organic Volatile Impurity Meets the requirement Sieve Test Min.98% through No.40 US Standard sieveSTABILITY Calcium Ascorbate is fairly stable to air if protected from humidity, but is slightly sensitive to heat; it is less susceptible to discoloration than ascorbic acid.BIOCHEMICAL EQUIVALENCE Because of differences in molecular weight the following equivalence exist between calcium Ascorbic and Ascorbic acid: 1 part Calcium Ascorbate = 0.82 part Ascorbic Acid 1 part Ascorbic Acid = 1.22 parts Calcium AscorbatePACKAGING & STORAGEStandard packing: 25-kilo drums or square pack boxes (palletized with polyethylene liners upon request). Store in tight, light-resistant containers. Avoid exposure to moisture and excessive heat. For optimum storage, maintain temperature at 72 deg.Fahrenheit or below.