Acetamiprid 20% SP, Acetamiprid 70%WP, Acetamiprid

Acetamiprid 20%SP, Acetamiprid 95% TC, Acetamiprid 70%WP Insecticide neonicotinoid Common name acetamiprid (pa ISO) IUPAC name (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine Chemical Abstracts name (E)-N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide CAS RN [135410-20-7] Development codes NI-25 (Nippon Soda) Acetamiprid APPLICATIONS Biochemistry Agonist of the nicotinic acetylcholine receptor, affecting the synapses in the insect central nervous system. Mode of action Systemic insecticide with translaminar activity and with contact and stomach action. Uses Control of Hemiptera, especially aphids, Thysanoptera and Lepidoptera, by soil and foliar application, on a wide range of crops, especially vegetables, fruit and tea. Applied at 75-300 g/ha on vegetables, 100-700 g/ha in orchards. Formulation types FU; GR; EC; WP. Selected tradenames: 'Mospilan' (Nippon Soda) Acetamiprid OTHER TRADENAMES 'Assail' (Aventis); 'Rescate' (Nippon Soda, Aventis); 'Saurus' (Nippon Soda, Aventis) Acetamiprid ANALYSIS Tech. product by hplc; residues by gc. Acetamiprid MAMMALIAN TOXICOLOGY Oral Acute oral LD50 for male rats 217, female rats 146, male mice 198, female mice 184 mg/kg. Skin and eye Acute percutaneous LD50 for male and female rats >2000 mg/kg. Non-irritating to skin and eyes (rabbits); not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for male and female rats >0.29 mg/l. NOEL (2 y) for rats 7.1 mg/kg b.w.; (18 mo) for mice 20.3 mg/kg b.w.; (1 y) for dogs 20 mg/kg b.w. Other Negative in the Ames test. Acetamiprid ECOTOXICOLOGY Birds LD50 for bobwhite quail 180 mg/kg. LC50 for bobwhite quail >5000 ppm. Fish LC50 (24-96 h) for carp >100 mg/l. Daphnia LC50 (24 h) >200 mg/l. Algae EC50 (72 h) >98.3 mg/l; NOEC (72 h) 98.3 mg/l. Acetamiprid ENVIRONMENTAL FATE Plants Slowly degraded on or in plants, forming five identified metabolites (H. Saito et al., Proc. 9th IUPAC Int. Congr. Pestic. Chem., London, 1998, 2, 5A-010). Soil/Environment DT50 in clay loam 1 d; in light clay 1-2 d. DT50 for total residues 15-30 d.