Pymetrozine

Pymetrozine: insecticide, pyridine Features: 1) Common name: pymetrozine 2) Structural formula: 3) Chemical name: 4,5-2H-6-methyl-4(3-pyridine-methano-amino)-1,2, 4-triadiazin-3-3(2H)-one 4) Molecular formula: C10H11N5O 5) Molecular weight: 217.2 6) CAS no.: 123312-89-0 Physical and chemical properties: 1) Appearance: colorless crystals 2) Melting point: 217oC 3) Vapor pressure: <4 x 10-3mPa (25oC) 4) KOWlogP: -0.18 5) Henry: <3.0 x 10-6Pa m3 mol-1 (calc.) 6) S.g./density: 1.36 (20oC) 7) Solubility: a) In water: 0.29g/L (pH 6.5. 25oC) b) In ethanol 2.25, hexane <0.001 (both in g/l. 20oC) 8) Stability: stable in air, hydrolysis DT50 4.3 h (pH 1), 25d (pH 5) Technical specifications: Pymetrozine 92% tech. specification: 1) Appearance: white to slightly yellow powder 2) a.i. content: >=92% 3) Insoluble matter in acetone: <=1.0% 4) Water: <=1.0% 5) PH: 6 - 9 6) Formulation types: WP; WG 7) Analysis: determination by HPLC and UV detection Applications: 1) Action: insecticide selective against homoptera, causing them to stop feeding. 2) Uses: a) Control of aphids and whitefly in vegetables, potatoes, ornamentals, cotton, deciduous and citrus fruit, tobacco, hops; both juvenile and adult stages are susceptible. Also for control of plant hoppers in rice b) Application rates vary from 150g/ha on potatoes to 200 - 300g/ha on ornamentals, tobacco and cotton; 10 - 30g/hl on vegetables, fruit and hops Toxicology: 1) Oral: acute oral LD50 for rats 5820mg/kg 2) Skin and eyes: acute percutaneous LD50 for rats >2000mg/kg. Non-irritating to the skin and eyes (rabbits). Not a skin sensitiser to guinea pigs. 3) Inhalation: LC50 (4h) >1800mg/m3 air 4) NOEL: (2y) for rats 3.7mg/kg b.w. daily 5) ADI: 0.03mg/kg b.w. 6) Other: non-mutagenic in 5 assay tests, including the Ames test 7) Birds: acute oral LD50 for bobwhite quails, mallard ducks >2000mg/kg. LC50 for bobwhite quails (8d) >5200ppm 8) Fish: LC50 (96h) for rainbow trout and common carp >100mg/L 9) Daphnia: LC50 (48h) 87mg/L 10) Algae: LC50 (72h) for scenedesmus subspicatus 47.1; LC50 (5d) for selenastrum capricornutum 21.7mg/L 11) Bees: oral LD50 (48h) >117 (Lig/bee; contact LD50 (48h)>200ig/bee 12) Worms: LC50 (14d) for eisenia foetlda 1098mg/kg soil Packaging: 25kg/plastic woven bag or cardboard drum lined with plastic bag