二乙基Toluamide

Diethyl ToluamideCAS #: 134-62-3Categories: InsecticidesDescription:NOMENCLATURE Common name: Diethyltoluamide IUPAC name: N,N-diethyl-m-toluamide Other names: DEET; N,N-Diethyl-3-Methylbenzamide; Diethyl Toluamide; Diethyl-M-Toluamide; 3-Methyl-N,N-Diethylbenzamide PHYSICAL CHEMISTRY Purity: 99% min.Appearance: achromatic or amber color liquid.S.g./density: 0.992 0.999/25,V.p: <0.01 mm Hg @25,B.p: 291.7 at 760 mm Hg,F.p: 155. Solubility: Soluble in most organic Solvents. Insoluble in water.APPLICATIONS Uses: Used as an insect repellent, as a resin solvent and in film formers. It is also used to impregnate clothing and as a leech repellent.MAMMALIAN TOXICOLOGY Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, skin: 500 mg Moderate; Inhalation, rat: LC50 = 5950 mg/m3; Oral, mouse: LD50 = 1470 mg/kg; Oral, rabbit: LD50 = 1584 mg/kg; Oral, rat: LD50 = 1950 mg/kg; Skin, rabbit: LD50 = 3180 uL/kg; Skin, rat: LD50 = 5 gm/kgECOTOXICOLOGY Fish toxicity: LC50 (96 hr) cichlid 120-150 ppm. After 96 hours, glutathione levels in liver, kidney and gills were raised. Invertebrate toxicity: EC50 (5 min) Photobacterium phosphoreum 67.9 ppm Microtox test.