吡虫啉

PHYSICAL AND CHEMICAL PROPERTIES: Appearance Colourless crystalis with a weak characteristic odour. M.p. 144? V.p 4×10 -7 mPa(20?) S.g./density 1.54(20?) Solubility In water 0.61g/L(20?).In dichloromethane 55,isopropanol 1.2,toluene 0.68,n-hexane<0.1(all in g/L,20?). Stability Stable to hydrolysis at pH5-11. TOXICOLOGY: Oral Acute oral LD 50 for male and female rats c.450,mice c.150mg/kg. Skin and eye Acute percutaneous LD 50 (24h) for rats >5000mg/kg,Non-irritating to eyes and skin(rabbits). Inhalation LC 50 (4h) for rats >5323mg/kg dust,69 mg/m 3 air (aerosol). NOEL (2) for male rats 100,female rats 300,mice 330mg/kg diet;(52w)for dogs 500mg/kg diet. ADI 0.057mg/kg b.w.. Other not mutagenic or teratogenic. Birds Acute oral LD 50 for Japanse quail 31mg/kg. Fish LD 50 (96h) for rainbow trout 211mg/L. Bees Harmful to honeybees by direct contact.